Blood Pressure

Blood pressure medications

Below are the most common types of Blood pressure mediaction

Beta blockers


These can help prevent angina and they may also reduce the risk of another heart attack if you have already had one. Symptoms of heart failure may be reduced with these drugs and some drugs in this group can help control an abnormal heart rhythm. They are also used as an additional medication to treat high blood pressure, where good control has not been achieved on two or more
other medications.

Drugs in this group: acebutolol, atenolol, bisoprolol, carvedilol, celiprolol, esmolol, labetalol, metoprolol, nadolol, nebivolol, oxprenolol, pindolol, propanolol, sotalol, timolol.

Side effects include: tiredness, coldness of the hands and feet, sleep
disturbances, increase in blood glucose levels, reduction in awareness
of hypoglycaemic symptoms, erectile dysfunction, low heart rate and
low blood pressure.

Diuretics


These are also known as ‘water tablets’ as they help the kidneys to pass more salt and water in to the urine, therefore making you need to urinate more often. Diuretics also help lower your blood pressure.

Drugs in this group: there are three main types of diuretic:
1. Thiazides: bendroflumethiazide, chlortalidone, cyclopenthiazide, indapamide, metolazone, xipamide.
2. Loop diuretics: bumetanide, furosemide, torasemide.
3. Potassium-sparing diuretics: amiloride, triamterene
and aldosterone antagonists: spironolactone, eplerenone.

Side effects of groups 1 and 2 include: increase in blood glucose levels, low levels of potassium (which can cause heart rhythm irregularities).
Side effects of group 3 include: stomach disturbances, raised potassium levels.

ACE inhibitors (Angiotensin converting enzyme)


These help to lower blood pressure and can help to delay the onset and progression of kidney damage (nephropathy). They work by blocking the action of an enzyme which is responsible for controlling blood pressure. By doing this, the constriction of blood vessels which increases blood pressure is relaxed, widening the arteries and in turn, reducing blood pressure. They are used in preventing and treating heart failure and may also be prescribed to people who have had a heart attack. You should have regular blood tests to check salt and potassium levels and kidney function.

Drugs in this group: captopril, cilazapril, enalapril, fosinopril, imidapril, moexipril, lisinopril, perindopril, quinapril, ramipril, trandolapril.

Side effects include: low blood pressure, persistent dry cough, change in sense of taste, dizziness, headaches, nausea, diarrhoea, skin rashes, decrease in kidney function.

Angiotensin II antagonists


These work similarly to ACE inhibitors and may often be used if you experience the dry cough associated with the ACE inhibitors. You should have regular blood tests to check your kidney function, salt and potassium levels.

Drugs in this group: candesartan, eprosartan, irbesartan, olmesartan, telmisartan, valsartan, losartan.

Side effects include: dizziness, low blood pressure.

Alpha-blockers


These work by relaxing the blood vessels and allowing blood to flow through more easily. These are useful as an alternative treatment when some other medications cannot be used, or as an addition to other blood pressure  treatments, when the blood pressure is more difficult to control.

Drugs in this group: doxazosin, indoramin, prazosin, terazosin.

Side effects include: postural hypotension (blood pressure falls too quickly when you stand up) causing dizziness, tiredness, palpitations, inability to control urination, erectile dysfunction.

Calcium channel blockers


These cause the arteries to relax and widen which allows blood to flow through more easily and reduces blood pressure. They also have an effect on the heart rate, whereby some will increase it and others decrease it.  They are used to treat angina and high blood pressure.

Drugs in this group: amlodipine, diltiazem, felodipine, isradipine, lacidipine, lercanidipine, nicardipine, nifedipine, nimodipine, nisoldipine, verapamil.

Side effects include: flushing, headache, dizziness, faintness, swelling in the ankles, stomach disturbances.