Tablets
Biguanide
Taken up to three times a day with, or immediately after a meal
Metformin works in two ways
- It helps to stop the liver producing new glucose
- It helps to overcome insulin resistance by making insulin carry glucose into muscle cells more effectively.
Side effects which may be experienced in this group
Nausea, vomiting, diarrhoea, abdominal pain, loss of appetite, (these often wear off after initial stages of treatment). Metallic taste, reduced absorption of vitamin B12, build up of lactic acid in the blood, allergic skin reaction, general allergic reaction, liver function problems.
| Name |
Trade name |
Initial daily dose |
Minimum/maximum
daily dose |
Metformin
(immediate release) |
Glucophage |
500 mg |
500-3000 mg |
|
Metformin
(prolonged release) |
Glucophage SR |
500 mg
750 mg |
500 mg - 2000 mg
750 - 1500mg (with evening meal) |
The dosage indicated will vary from person to person.
If you have any problems with your dosage or the tablets you are taking, contact your healthcare team.
Next review date September 2009