Our research projects

We fund world class research

At any one time, we have around 120 research projects making discoveries across the UK. Each of these projects is only possible thanks to the generous support of our members, donors and local groups

Every project is reviewed by experts and approved by our research committee and our panel of people living with diabetes. So you're supporting research of the highest scientific quality, led by researchers with the skills and experience to succeed.

Your support of our research projects means we can keep tackling the complications of diabetes and bring us one step closer to a cure.

Find a research project

Use the search tool to discover research taking place in your local area, or choose a subject or type of diabetes you’re interested in.

Each project page showcases the details of the research, and if you find a research project you could really get behind, you can support it in lots of different ways.

58 results found

Filters
Research Area
Region
Subject

Why does insulin resistance occur in Type 2 diabetes?

Project:
Northern & Yorkshire - Leeds
Status:
Project available for adoption
Tags:
England
Northern & Yorkshire
Type 2
Causes
Project Summary

Insulin resistance is a key feature of Type 2 diabetes. It affects the ability of the body’s cells to take in glucose and causes high blood glucose levels.

Professor Bryant will explore whether proteins involved in this process don’t work properly in people with Type 2 diabetes. This research could improve our understanding of what causes Type 2 diabetes and how to treat it.

Lymphatics: a new treatment target for kidney disease in people with diabetes?

Project:
London
Status:
Project available for adoption
Tags:
Complications
London
England
Type 1 and Type 2
Project Summary

Dr David Long and his colleagues are investigating the function of kidney lymphatic vessels in diabetic kidney disease. This will help us to understand whether targeting lymphatic vessels could be a novel treatment strategy for diabetic kidney disease. 

Targeted treatment for Type 2 risk

Project:
London
Status:
Project has less than a year to run
Tags:
Type 2
London
England
Prevention
Project Summary

Dr Nicola Guess will investigate the benefits of targeted treatment for different groups of people at high risk of Type 2 diabetes.

She will use the dietary carbohydrate ‘inulin’ to try and improve glucose and insulin levels in people unlikely to benefit from changes to diet and physical activity levels.

Not all fat’s the same: protecting against Type 2 diabetes

Project:
Northern & Yorkshire - Leeds
Status:
Project available for adoption
Tags:
Northern & Yorkshire
England
Type 2
Causes
Project Summary

Dr Roberts is focusing on fat cells, with different types responsible for storing and burning fat. He hopes to find specific signals from ‘good’ beige fat cells, to see if they can improve fat metabolism and protect the body from Type 2 diabetes.

If successful, this research could inform the development of new protective Type 2 diabetes treatments.

Investigating a potential cause of Type 1 diabetes

Project:
South West - Exeter
Status:
Project not available for adoption
Tags:
Causes
Type 1
England
South West
Project Summary

It’s believed that one of the factors involved in the development of Type 1 diabetes could be a specific type of virus that infects pancreatic beta cells, causing the immune system to attack them. The aim of this project is to investigate key proteins that may be involved in the potential viral infection of beta cells.

The results will improve our understanding of the causes of Type 1 diabetes, ultimately informing future research into the prevention and treatment of the condition. 

Follicular helper T cells: are they an indication of Type 1 diabetes?

Project:
London
Status:
Project not available for adoption
Tags:
Type 1
London
England
Prevention
Towards a cure
Partnership
Project Summary

Professor Lucy Walker and her colleagues have found that a specific type of immune cell – called the follicular helper T cell – can trigger Type 1 diabetes in mice, and is more common in people with Type 1 diabetes.

The team now aims to understand exactly how follicular helper T cells cause Type 1 diabetes, and they will test new strategies to stop this from happening. They will test whether follicular helper T cells can be used as an early indication of the autoimmune response in Type 1 diabetes.

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