Our research projects

We fund world class research

At any one time, we have around 120 research projects making discoveries across the UK. Each of these projects is only possible thanks to the generous support of our members, donors and local groups

Every project is reviewed by experts and approved by our research committee and our panel of people living with diabetes. So you're supporting research of the highest scientific quality, led by researchers with the skills and experience to succeed.

Your support of our research projects means we can keep tackling the complications of diabetes and bring us one step closer to a cure.

Find a research project

Use the search tool to discover research taking place in your local area, or choose a subject or type of diabetes you’re interested in.

Each project page showcases the details of the research, and if you find a research project you could really get behind, you can support it in lots of different ways.

53 results found

Filters
Research Area
Region
Subject

Why does insulin resistance occur in Type 2 diabetes?

Project:
Northern & Yorkshire - Leeds
Status:
Project available for adoption
Tags:
England
Northern & Yorkshire
Type 2
Causes
Project Summary

Insulin resistance is a key feature of Type 2 diabetes. It affects the ability of the body’s cells to take in glucose and causes high blood glucose levels.

Professor Bryant will explore whether proteins involved in this process don’t work properly in people with Type 2 diabetes. This research could improve our understanding of what causes Type 2 diabetes and how to treat it.

Testing blood glucose in a flash

Project:
North West - Manchester
Status:
Project available for adoption
Tags:
Healthcare
Type 1
North West
England - North West
England
Project Summary

Flash glucose monitoring gives people with diabetes a simple and painless way to monitor their blood glucose levels. But not everyone who would benefit has access to this life-changing technology. Dr Lalantha Leelarathna will compare the impact and costs of Flash 2 to finger pricks tests in people with Type 1 diabetes. This will provide important evidence that could help make Flash more widely available on the NHS, to transform the lives of people with Type 1 diabetes.

What aspects of Type 2 diabetes might lead to dementia?

Project:
London
Status:
Project available for adoption
Tags:
Type 2
Complications
London
England
Project Summary

Having type 2 diabetes increases the risk of dementia, but we don’t know why. Dr Eszter Vamos and her team want to find out which diabetes-related factors are involved in the development of dementia, like blood glucose, blood pressure and cholesterol levels. This will help us to find new ways to protect people with type 2 diabetes from dementia.

Understanding how beta cells release insulin

Project:
South East
Status:
Project available for adoption
Tags:
Type 2
South East
England
Healthcare
Project Summary

Beta cells release insulin into the blood stream, but this complex process isn’t well understood. Dr Benoit Hastoy wants to investigate the process in more detail, to try and improve the effectiveness of existing treatments for people with Type 2 diabetes.

GLUT Instinct: How do fat cells control blood sugar levels?

Project:
South West
Status:
Project has less than a year to run
Tags:
Type 2
Causes
South West
England
Project Summary

Muscle and fat cells absorb sugar from the blood, using an important protein called GLUT4. But we don’t completely understand how GLUT4 is controlled. Dr Koumanov believes it could be a newly discovered protein called retriever, so she wants to study fat cells to find out for certain. If successful, these findings could help scientists to develop new ways to prevent or treat Type 2 diabetes

Lymphatics: a new treatment target for kidney disease in people with diabetes?

Project:
London
Status:
Project not available for adoption
Tags:
Complications
London
England
Type 1 and Type 2
Project Summary

Dr David Long and his colleagues are investigating the function of kidney lymphatic vessels in diabetic kidney disease. This will help us to understand whether targeting lymphatic vessels could be a novel treatment strategy for diabetic kidney disease. 

Superior screening for gestational diabetes

Project:
London
Status:
Project has less than a year to run
Tags:
Other
London
England
Project Summary

Dr Sara White will develop a new test for effective early identification of women who are at risk of gestational diabetes. The test could be available within three years, help to reduce the number of women who develop gestational diabetes and improve health outcomes for mothers and their children.

Not all fat’s the same: protecting against Type 2 diabetes

Project:
Northern & Yorkshire - Leeds
Status:
Project available for adoption
Tags:
Northern & Yorkshire
England
Type 2
Causes
Project Summary

Dr Roberts is focusing on fat cells, with different types responsible for storing and burning fat. He hopes to find specific signals from ‘good’ beige fat cells, to see if they can improve fat metabolism and protect the body from Type 2 diabetes.

If successful, this research could inform the development of new protective Type 2 diabetes treatments.

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