Save for later

Our research projects

With more lives to change than ever, we can't stop now.

At any one time, we have around 120 research projects making discoveries across the UK. Each of these projects is only possible thanks to the generous support of our members, donors and local groups.

Your support means we can keep tackling the complications of diabetes and bring us one step closer to a cure.

We fund world class research

Our research studies are reviewed by experts and approved by the Diabetes UK Research Committee and our panel of people living with diabetes. So you're supporting research of the highest scientific quality, led by researchers with the skills and experience necessary to succeed.

Find a research project

You can use the box below to search for projects by the type of research involved or the region or research centre where they are taking place.

We invite you to read about the studies that interest you and to consider supporting them through our Adopt a Project scheme. Each project page includes details on whether a project is available to adopt and how long it has left to run. A showcase of all our research projects is also available to download.

22 results found

Lymphatics: a new treatment target for kidney disease in people with diabetes?

Project:
London
Status:
Project available for adoption
Tags:
Complications
Project Summary

Dr David Long and his colleagues are investigating the function of kidney lymphatic vessels in diabetic kidney disease. This will help us to understand whether targeting lymphatic vessels could be a novel treatment strategy for diabetic kidney disease. 

Targeted treatment for Type 2 risk

Project:
London
Status:
Project has less than a year to run
Tags:
Prevention
Project Summary

Dr Nicola Guess will investigate the benefits of targeted treatment for different groups of people at high risk of Type 2 diabetes.

She will use the dietary carbohydrate ‘inulin’ to try and improve glucose and insulin levels in people unlikely to benefit from changes to diet and physical activity levels.

Follicular helper T cells: are they an indication of Type 1 diabetes?

Project:
London
Status:
Project available for adoption
Tags:
Prevention
Towards a cure
Partnership
Project Summary

Professor Lucy Walker and her colleagues have found that a specific type of immune cell – called the follicular helper T cell – can trigger Type 1 diabetes in mice, and is more common in people with Type 1 diabetes.

The team now aims to understand exactly how follicular helper T cells cause Type 1 diabetes, and they will test new strategies to stop this from happening. They will test whether follicular helper T cells can be used as an early indication of the autoimmune response in Type 1 diabetes.

Can self-management therapies help with chronic pain?

Project:
London
Status:
Project available for adoption
Tags:
Complications
Partnership
Project Summary

Current treatment options for chronic pain in diabetes (also called painful diabetic neuropathy) are not very effective. A PhD student in Professor McCracken’s lab will investigate whether self-management strategies that focus around psychology could be used to manage pain better.

If successful, it will form a base for developing psychological therapies for people with painful diabetic neuropathy.

A new ADDRESS for Type 1 trial recruitment

Project:
London
Status:
Project not available for adoption
Tags:
Project Summary

Professor Desmond Johnston and his team will work closely with researchers across the UK to increase the value of ADDRESS (the After Diabetes Diagnosis Research Support System), which helps to recruit people newly diagnosed with Type 1 diabetes and their families into trials of new immune therapies. 

Helper molecules to improve islet transplant

Project:
London
Status:
Project not available for adoption
Tags:
Project Summary

Professor Peter Jones and his team will find out which molecules allow a particular kind of ‘helper cell’ to improve islet transplants.

Such molecules could be combined with islet transplants to improve their outcomes for people with Type 1 diabetes and make them more widely available.

Can chilli treat chronic foot pain?

Project:
London
Status:
Project available for adoption
Tags:
Complications
Project Summary

Chronic pain in the feet, caused by nerve damage, is a debilitating complication of Type 1 or Type 2 diabetes. Professor Anand will test if a new treatment (called the capsaicin 8 percent patch) can reduce pain and potentially reverse nerve damage. If successful, this treatment could help to reduce the effects of chronic pain and improve quality of life in people with diabetes.

Boosting beta cell growth and survival

Project:
London
Status:
Project not available for adoption
Tags:
Innovation
Project Summary

Dr Bo Liu will study the role of molecules called microRNAs in the growth and survival of insulin-producing beta cells. She aims to find out if beta cell growth can be promoted by manipulating these molecules and/or other factors that the microRNAs interact with.

Her work could help to support the development of new therapies for Type 1 and Type 2 diabetes.

Monogenic diabetes and pancreatic tumours

Project:
London
Status:
Project available for adoption
Tags:
Rare types of diabetes
Project Summary

Dr Iacovazzo is studying a rare type of diabetes that occurs at the same time as tumours appear in the pancreas. Previous research has found a specific genetic mutation that may be behind this condition, and this study aims to confirm whether this is the case.

If successful, this project will improve our understanding of this rare condition and help to identify people at risk of developing it.

Brand Icons/Telephone check - FontAwesome icons/tick icons/uk