Our research projects

We fund world class research

At any one time, we have around 120 research projects making discoveries across the UK. Each of these projects is only possible thanks to the generous support of our members, donors and local groups

Every project is reviewed by experts and approved by our research committee and our panel of people living with diabetes. So you're supporting research of the highest scientific quality, led by researchers with the skills and experience to succeed.

Your support of our research projects means we can keep tackling the complications of diabetes and bring us one step closer to a cure.

Find a research project

Use the search tool to discover research taking place in your local area, or choose a subject or type of diabetes you’re interested in.

Each project page showcases the details of the research, and if you find a research project you could really get behind, you can support it in lots of different ways.

12 results found

Filters
Research Area
Region
Subject

Ancient medicine to treat infected foot ulcers

Project:
Midlands - Warwick
Status:
Project available for adoption
Tags:
Midlands
Type 1 and Type 2
Complications
Project Summary

Infections in foot ulcers can be hard to treat and don’t always respond to antibiotics. If this happens, they can result in amputations or sepsis.

Dr Freya Harrison wants to find new types of antibiotics that could be used to effectively treat infections in foot ulcers. In the future, this could improve the quality of people with diabetes’ lives and reduce the number of amputations.

Benefits of exercise for Type 2 diabetes

Project:
Midlands - Nottingham
Status:
Project not available for adoption
Tags:
Innovation
England
Midlands
Type 2
Healthcare
Project Summary

Exercise is known to provide health benefits for people living with Type 2 diabetes and reduce the risk of developing Type 2. But we don’t yet understand why.

Dr Daniel Wilkinson hopes to understand what’s going on inside the body during exercise and why it has positive effects on our health. In the long term, this could help to develop new drugs which also provide these benefits for people with Type 2 diabetes. 

Keeping kidney cells talking

Project:
Midlands - Lincoln
Status:
Project available for adoption
Tags:
Complications
Type 1 and Type 2
Midlands
Project Summary

Dr Hills wants to understand why kidney cells can’t function properly in people with diabetes. She’ll be looking at how high glucose levels, combined with a specific stress molecule, change the behaviour of kidney cells. This study could help to identify new drugs to prevent or treat kidney disease in the future.

Why is exercise good for people with Type 2 diabetes?

Project:
Birmingham, Midlands
Status:
Project available for adoption
Tags:
Healthcare
Type 2
Midlands
England
Innovation
Project Summary

We know that exercise is good for people with Type 2 diabetes, but Dr Barlow would like to understand the relationship between the two better. He’ll look at the direct effects of muscle contraction on insulin-producing beta cells in the pancreas, to find out exactly why exercise is beneficial for people with Type 2 diabetes and how this could be maximised in the future.

Small molecules to stop the immune attack

Project:
Midlands - Birmingham
Status:
Project available for adoption
Tags:
Towards a cure
England - Midlands
Midlands
Type 1
Project Summary

In Type 1 diabetes, immune cells called T cells attack and destroy insulin-producing beta cells in the pancreas. T cells recognise five specific molecules on beta cells, and Dr Parth Narendran wants to identify the exact regions of the molecules involved. This could help scientists to develop more accurate diagnosis tools, and find ways to prevent Type 1 or stop it progressing. 

Trading ‘bad’ fats for ‘good’ fats in Type 2

Project:
Midlands - Warwick
Status:
Project not available for adoption
Tags:
Causes
Type 2
Midlands
England
Project Summary

Professor Zammit and his team aim to find out if enzymes that produce fat in the muscle determine whether it is 'good' fat (seen in athletes) or 'bad' fat (seen in many people with Type 2 diabetes). They will also see if altering the route by which muscle fat is produced might help to prevent or reduce insulin resistance and Type 2 diabetes.

Fatty livers and gestational diabetes

Project:
Midlands - Stoke-on-Trent
Status:
Project not available for adoption
Tags:
Pregnancy
Midlands
England
Type 2
Other
Project Summary

Gestational diabetes can increase the risk of Type 2 diabetes in later life, as can high levels of fat in the liver. Dr Hanna is testing a screening programme, to see if women with gestational diabetes and high levels of fat in the liver are at a higher risk of Type 2 diabetes overall. If so, this group of women could be supported to reduce their risk.

Finding new ways to stop diabetes-related kidney damage

Project:
Midlands - Lincoln
Status:
Project available for adoption
Tags:
Complications
Midlands
England
Type 1 and Type 2
Project Summary

Many people with diabetes experience nephropathy – a condition that is the leading cause of end-stage kidney disease. We know that high levels of glucose can damage kidney cells, and Professor Squires hopes to find ways to stop or prevent this damage from happening. These could be developed into treatments for diabetes-related nephropathy in the future.

Can stress hormones protect beta cells?

Project:
Midlands - Birmingham
Status:
Project available for adoption
Tags:
Midlands
Type 2
England
Innovation
Project Summary

Professor David Hodson would like to understand how stress hormones, called glucocorticoids, affect insulin-producing beta cells in the pancreas. Understanding how these stress hormones might be linked to Type 2 diabetes might uncover new ways to treat the condition in the future.

Fatty livers and gestational diabetes

Project:
Midlands
Status:
Project available for adoption
Tags:
England - Midlands
Midlands
Pregnancy
Project Summary

Gestational diabetes can increase the risk of Type 2 diabetes in later life, as can high levels of fat in the liver. Dr Hanna is testing a screening programme, to see if women with gestational diabetes and high levels of fat in the liver are at a higher risk of Type 2 diabetes overall. If so, this group of women could be supported to reduce their risk. 

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