Our research projects

We fund world class research

At any one time, we have around 120 research projects making discoveries across the UK. Each of these projects is only possible thanks to the generous support of our members, donors and local groups

Every project is reviewed by experts and approved by our research committee and our panel of people living with diabetes. So you're supporting research of the highest scientific quality, led by researchers with the skills and experience to succeed.

Your support of our research projects means we can keep tackling the complications of diabetes and bring us one step closer to a cure.

Find a research project

Use the search tool to discover research taking place in your local area, or choose a subject or type of diabetes you’re interested in.

Each project page showcases the details of the research, and if you find a research project you could really get behind, you can support it in lots of different ways.

9 results found

Filters
Research Area
Region
Subject

Untangling the link between Type 2 diabetes and Alzheimer's disease

Project:
South East - Southampton
Status:
Project available for adoption
Tags:
England - South East
South East
Complications
Type 2
Project Summary

People with Type 2 diabetes have an increased risk of developing Alzheimer’s disease, but we don’t know why. Dr Mudher believes that Type 2 diabetes could have a negative effect on a protein in the brain, called ‘Tau’. She wants to find out more about this interaction to see if it can be stopped, to reduce the risk of Alzheimer’s disease in people with Type 2 diabetes.

What’s the link between ageing and Type 2 diabetes?

Project:
South East
Status:
Project available for adoption
Tags:
Type 2
England - South East
South East
Causes
Partnership
Project Summary

Changes to our insulin-producing beta cells that happen as we get older are linked to Type 2 diabetes, but we don’t yet know how or why. Professor Masashi Narita will study cells in the lab to shed light on this link. In the future, this could lead to the development of new treatments to combat the effects of ageing on beta cells, and help to prevent Type 2 diabetes.

Understanding how beta cells release insulin

Project:
South East
Status:
Project available for adoption
Tags:
Type 2
South East
England
Healthcare
Project Summary

Beta cells release insulin into the blood stream, but this complex process isn’t well understood. Dr Benoit Hastoy wants to investigate the process in more detail, to try and improve the effectiveness of existing treatments for people with Type 2 diabetes.

Using artificial intelligence to predict foot pain

Project:
South East - Oxford
Status:
Project available for adoption
Tags:
South East
Type 1
Type 2
Type 1 and Type 2
Complications
Project Summary

People with diabetes can develop problems with their feet, called neuropathy. Some people experience chronic pain alongside this, but we don’t yet know why. Professor David Bennet will use machine learning to identify risk factors for painful neuropathy and develop a ‘calculator’ that could help to spot people at risk. This research could help to develop new treatments and allow doctors to better support those at greatest risk.

Why do bone cells age earlier in Type 1 diabetes?

Project:
South East
Status:
Project available for adoption
Tags:
Type 1
Complications
England - South East
South East
Partnership
Project Summary

Bone cells appear to age earlier in people with Type 1 diabetes, which can make bone fractures more likely. Professor Lynne Cox wants to find the root cause of why bone cells age, and develop treatments that improve bone strength and prevent fractures. This could help people with Type 1 diabetes to stay healthy as they get older.

A potential treatment for extreme insulin resistance

Project:
Eastern - Cambridge
Status:
Project not available for adoption
Tags:
Other
South East
England
Eastern
Rare types of diabetes
Project Summary

Dr Robert Semple and his team will develop and evaluate the potential of proteins called antibodies for treating people with a type of extreme insulin resistance caused by rare genetic changes.

They will also develop a diagnostic screening test that will identify people that are likely to respond to the therapeutic antibody treatment.

Gestational diabetes and the long-term health of offspring

Project:
South East
Status:
Project not available for adoption
Tags:
South East
England
Pregnancy
Other
Project Summary

Professor Lillycrop is studying the genes of babies from mothers with and without gestational diabetes, to look for specific genetic changes that come about as a result of gestational diabetes.

She hopes to find out whether those genetic changes have an impact on the long-term health of the babies, and whether treatments to prevent the changes to genes from happening can be developed.

Understanding glucagon in Type 2

Project:
South East - Oxford
Status:
Project available for adoption
Tags:
Innovation
South East
England
Type 2
Project Summary

Dr Quan Zhang will use advanced techniques to study mechanisms involved in the release of glucagon (the hormone that raises blood glucose when it falls too low) and find out how they become disrupted in diabetes.

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