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Our research projects

We fund world class research

At any one time, we have around 120 research projects making discoveries across the UK. Each of these projects is only possible thanks to the generous support of our members, donors and local groups

Every project is reviewed by experts and approved by our research committee and our panel of people living with diabetes. So you're supporting research of the highest scientific quality, led by researchers with the skills and experience to succeed.

Your support of our research projects means we can keep tackling the complications of diabetes and bring us one step closer to a cure.
 

Find a research project

Use the search tool to discover research taking place in your local area, or choose a subject or type of diabetes you’re interested in.

Each project page showcases the details of the research, and if you find a research project you could really get behind, you can support it in lots of different ways.

26 results found

Investigating a potential cause of Type 1 diabetes

Project:
South West - Exeter
Status:
Project available for adoption
Tags:
Causes
Project Summary

It’s believed that one of the factors involved in the development of Type 1 diabetes could be a specific type of virus that infects pancreatic beta cells, causing the immune system to attack them. The aim of this project is to investigate key proteins that may be involved in the potential viral infection of beta cells.

The results will improve our understanding of the causes of Type 1 diabetes, ultimately informing future research into the prevention and treatment of the condition. 

Down to details of Type 1 immune attack

Project:
South West - Bristol
Status:
Project available for adoption
Tags:
Causes
Project Summary

In Type 1 diabetes, the immune system mistakenly attacks several different proteins in the pancreas. One of them is called ZnT8. It seems that people develop Type 1 diabetes at a slower rate if their immune system attacks ZnT8. Dr Gillespie would like to understand the biology behind this attack.

This project will help us understand Type 1 diabetes in more detail and may help researchers develop new therapies to stop the immune attack.

Follicular helper T cells: are they an indication of Type 1 diabetes?

Project:
London
Status:
Project not available for adoption
Tags:
Prevention
Towards a cure
Partnership
Project Summary

Professor Lucy Walker and her colleagues have found that a specific type of immune cell – called the follicular helper T cell – can trigger Type 1 diabetes in mice, and is more common in people with Type 1 diabetes.

The team now aims to understand exactly how follicular helper T cells cause Type 1 diabetes, and they will test new strategies to stop this from happening. They will test whether follicular helper T cells can be used as an early indication of the autoimmune response in Type 1 diabetes.

Testing blood glucose in a flash

Project:
North West - Manchester
Status:
Project available for adoption
Tags:
Healthcare
Project Summary

Flash Glucose Monitoring gives people with diabetes a simple and painless way to monitor their blood glucose levels. But not everyone who would benefit has access to this life-changing technology. Dr Lalantha Leelarathna will compare the impact and costs of Flash to finger pricks tests in people with Type 1 diabetes. This will provide important evidence that could help make Flash more widely available on the NHS, to transform the lives of people with Type 1 diabetes.

The impact of islet transplantation

Project:
England - Newcastle
Status:
Project available for adoption
Tags:
Towards a cure
Project Summary

Professor James Shaw and his team will examine the effectiveness of islet transplants at different UK transplant centres, and the impact they can have on the wellbeing people living with Type 1 diabetes who have hypo unawareness. The team hope to gain a better understanding of which methods lead to the most successful transplants, and who could benefit the greatest in the long-term.

Exploring blood glucose control in Type 1 diabetes

Project:
Scotland - Edinburgh
Status:
Project is fully funded
Tags:
Healthcare
Project Summary

Professor Colhoun hopes to understand how blood glucose control in Type 1 diabetes changes over time in different groups of people. These insights could help us find ways to improve blood glucose levels in people with Type 1 diabetes.

Stopping thymic B cells in Type 1 diabetes

Project:
Northern & Yorkshire - York
Status:
Project available for adoption
Tags:
Causes
Project Summary

The thymus helps to destroy ‘bad’ immune cells that attack the body, but this doesn’t happen in people with Type 1 diabetes. Dr Allison Green will find out why and how the thymus stops working properly in people with Type 1 diabetes, which could lead to treatments to prevent the condition.

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