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Our research projects

With more lives to change than ever, we can't stop now.

At any one time, we have around 120 research projects making discoveries across the UK. Each of these projects is only possible thanks to the generous support of our members, donors and local groups.

Your support means we can keep tackling the complications of diabetes and bring us one step closer to a cure.

We fund world class research

Our research studies are reviewed by experts and approved by the Diabetes UK Research Committee and our panel of people living with diabetes. So you're supporting research of the highest scientific quality, led by researchers with the skills and experience necessary to succeed.

Find a research project

You can use the box below to search for projects by the type of research involved or the region or research centre where they are taking place.

We invite you to read about the studies that interest you and to consider supporting them through our Adopt a Project scheme. Each project page includes details on whether a project is available to adopt and how long it has left to run. A showcase of all our research projects is also available to download.

26 results found

Exploring blood glucose control in Type 1 diabetes

Project:
Scotland - Edinburgh
Status:
Project is fully funded
Tags:
Project Summary

Professor Colhoun hopes to understand how blood glucose control in Type 1 diabetes changes over time in different groups of people. These insights could help us find ways to improve blood glucose levels in people with Type 1 diabetes.

Follow-up of teens with Type 1 from the AdDIT trial

Project:
Eastern - Cambridge
Status:
Project not available for adoption
Tags:
Project Summary

Professor David Dunger and his team will continue to follow-up adolescents with Type 1 diabetes who were involved in the AdDIT trial to assess the long-term effects of drugs which lower blood pressure and cholesterol levels on the development of diabetes complications.

The follow-up will also allow them to identify new risk markers for complications and potentially alternative interventions.

Investigating a potential cause of Type 1 diabetes

Project:
South West - Exeter
Status:
Project available for adoption
Tags:
Causes
Project Summary

It’s believed that one of the factors involved in the development of Type 1 diabetes could be a specific type of virus that infects pancreatic beta cells, causing the immune system to attack them. The aim of this project is to investigate key proteins that may be involved in the potential viral infection of beta cells.

The results will improve our understanding of the causes of Type 1 diabetes, ultimately informing future research into the prevention and treatment of the condition. 

Follicular helper T cells: are they an indication of Type 1 diabetes?

Project:
London
Status:
Project available for adoption
Tags:
Prevention
Towards a cure
Partnership
Project Summary

Professor Lucy Walker and her colleagues have found that a specific type of immune cell – called the follicular helper T cell – can trigger Type 1 diabetes in mice, and is more common in people with Type 1 diabetes.

The team now aims to understand exactly how follicular helper T cells cause Type 1 diabetes, and they will test new strategies to stop this from happening. They will test whether follicular helper T cells can be used as an early indication of the autoimmune response in Type 1 diabetes.

Down to details of Type 1 immune attack

Project:
South West - Bristol
Status:
Project available for adoption
Tags:
Causes
Project Summary

In Type 1 diabetes, the immune system mistakenly attacks several different proteins in the pancreas. One of them is called ZnT8. It seems that people develop Type 1 diabetes at a slower rate if their immune system attacks ZnT8. Dr Gillespie would like to understand the biology behind this attack.

This project will help us understand Type 1 diabetes in more detail and may help researchers develop new therapies to stop the immune attack.

Using genetics to predict Type 1 diabetes

Project:
South West - Exeter
Status:
Project available for adoption
Tags:
Causes
Project Summary

There is a time window of several years between the start of the Type 1 diabetes immune attack and the appearance of symptoms.

Dr Richard Oram has developed a ‘risk calculator’ that uses information from genes linked to Type 1 diabetes to potentially find those at risk of the condition. Now, they want to test the calculator using data from several large studies.

This could help to find people at high risk of Type 1 diabetes in the future, and provide vital knowledge to help create treatments to stop it.

Stopping thymic B cells in Type 1 diabetes

Project:
Northern & Yorkshire - York
Status:
Project available for adoption
Tags:
Causes
Project Summary

The thymus helps to destroy ‘bad’ immune cells that attack the body, but this doesn’t happen in people with Type 1 diabetes. Dr Allison Green will find out why and how the thymus stops working properly in people with Type 1 diabetes, which could lead to treatments to prevent the condition.

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