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Our research projects

We fund world class research

At any one time, we have around 120 research projects making discoveries across the UK. Each of these projects is only possible thanks to the generous support of our members, donors and local groups

Every project is reviewed by experts and approved by our research committee and our panel of people living with diabetes. So you're supporting research of the highest scientific quality, led by researchers with the skills and experience to succeed.

Your support of our research projects means we can keep tackling the complications of diabetes and bring us one step closer to a cure.
 

Find a research project

Use the search tool to discover research taking place in your local area, or choose a subject or type of diabetes you’re interested in.

Each project page showcases the details of the research, and if you find a research project you could really get behind, you can support it in lots of different ways.

5 results found

The cost-effectiveness of DiRECT’s Type 2 remission

Project:
Scotland - Glasgow
Status:
Project not available for adoption
Tags:
Remission
Project Summary

The DiRECT trial is finding out whether a weight management programme, including a low-calorie diet, can put Type 2 diabetes into remission for the long-term. This project will look at the cost effectiveness of this programme when delivered through GP care.

This will give the NHS important information to help work out if this kind of treatment could be offered to people with Type 2 diabetes in the future. 

The DiRECT route to Type 2 remission?

Project:
Scotland (Glasgow), and Northern and Yorkshire (Newcastle)
Status:
Project available for adoption
Tags:
Remission
Project Summary

With support from our largest ever research grant, Professors Mike Lean and Roy Taylor will investigate if a low-calorie diet, alongside weight management support, can put Type 2 diabetes into remission for the long-term. 

Their vital work will find out if a low-calorie, diet-based treatment should be offered as a routine treatment for Type 2 diabetes. In the future, this could help to reduce the number of people living with Type 2 diabetes.

Get all the latest news on how the low-calorie diet research is going so far.

Can combinations of gut hormones treat Type 2 diabetes?

Project:
London
Status:
Project is fully funded
Tags:
Remission
Partnership
Project Summary

Obesity is the biggest risk factor of Type 2 diabetes, and bariatric surgery is currently an effective treatment. A rise in the levels of particular gut hormones are seen following surgery, and Dr Salem has found that the beneficial effects of the surgery can be replicated using the gut hormones alone in animal models.

During her fellowship, Dr Salem plans to explore the underlying biology of how gut hormones effectively treat diabetes and obesity, to inform the development of combination hormone treatments that could result in diabetes remission and sustained weight loss.

ReTUNEing Type 2 diabetes remission

Project:
Northern & Yorkshire - Newcastle
Status:
Project available for adoption
Tags:
Remission
Project Summary

Obesity is a key risk factor for Type 2 diabetes, but not everyone with this condition is overweight.

Professor Taylor will study whether weight loss in people with Type 2 diabetes who aren’t obese can put their condition into remission. If the researchers confirm this, it could change the advice given to people with Type 2 of a normal weight and help them live well for longer.  

Keeping Type 2 diabetes in remission: DiRECT extension

Project:
Scotland
Status:
Project available for adoption
Tags:
Remission
Project Summary

The DiRECT trial is finding out whether a weight management programme, including a low-calorie diet, can put Type 2 diabetes into remission. This project will extend DiRECT for a further three years, to see if this approach can keep Type 2 in remission for the long-term. This work could potentially transform the way Type 2 diabetes is managed in the future, and could have enormous benefits for people living with the condition.

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