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Our research projects

With more lives to change than ever, we can't stop now.

At any one time, we have around 120 research projects making discoveries across the UK. Each of these projects is only possible thanks to the generous support of our members, donors and local groups.

Your support means we can keep tackling the complications of diabetes and bring us one step closer to a cure.

We fund world class research

Our research studies are reviewed by experts and approved by the Diabetes UK Research Committee and our panel of people living with diabetes. So you're supporting research of the highest scientific quality, led by researchers with the skills and experience necessary to succeed.

Find a research project

You can use the box below to search for projects by the type of research involved or the region or research centre where they are taking place.

We invite you to read about the studies that interest you and to consider supporting them through our Adopt a Project scheme. Each project page includes details on whether a project is available to adopt and how long it has left to run. A showcase of all our research projects is also available to download.

5 results found

Targeted treatment for Type 2 risk

Project:
London
Status:
Project has less than a year to run
Tags:
Prevention
Project Summary

Dr Nicola Guess will investigate the benefits of targeted treatment for different groups of people at high risk of Type 2 diabetes.

She will use the dietary carbohydrate ‘inulin’ to try and improve glucose and insulin levels in people unlikely to benefit from changes to diet and physical activity levels.

Follicular helper T cells: are they an indication of Type 1 diabetes?

Project:
London
Status:
Project available for adoption
Tags:
Prevention
Towards a cure
Partnership
Project Summary

Professor Lucy Walker and her colleagues have found that a specific type of immune cell – called the follicular helper T cell – can trigger Type 1 diabetes in mice, and is more common in people with Type 1 diabetes.

The team now aims to understand exactly how follicular helper T cells cause Type 1 diabetes, and they will test new strategies to stop this from happening. They will test whether follicular helper T cells can be used as an early indication of the autoimmune response in Type 1 diabetes.

Gene therapy to target T cells in Type 1

Project:
Cardiff, Wales
Status:
Project not available for adoption
Tags:
Prevention
Towards a cure
Project Summary

In Type 1 diabetes, T cells of the immune system destroy insulin-producing cells in the pancreas. Professor Susan Wong will work to develop a gene therapy to encourage the body’s own immune system to destroy the ‘bad’ T cells and protect against Type 1 diabetes.

Combining exercise with medication to prevent Type 2

Project:
Northern & Yorkshire - Liverpool
Status:
Project available for adoption
Tags:
Prevention
Project Summary

Being overweight or obese can lead to a high risk of Type 2 diabetes. Professor Wagenmakers wants to develop a lifestyle intervention for people at high risk of Type 2, combining regular exercise with a blood fat-lowering prescription drug. He hopes this will be a successful strategy for preventing or delaying Type 2 diabetes in people at high risk.

Thinking outside the BOX

Project:
South West - Bristol
Status:
Project available for adoption
Tags:
Causes
Prevention
Project Summary

Dr Kathleen Gillespie will extend the existing Bart’s–Oxford study, the world’s longest running family study of Type 1 diabetes. Her work will provide a unique resource of biological samples, to enable scientists to study the genetic risk factors, environmental influences and their impact on the immune system in Type 1 diabetes.

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