Our research projects

We fund world class research

At any one time, we have around 120 research projects making discoveries across the UK. Each of these projects is only possible thanks to the generous support of our members, donors and local groups

Every project is reviewed by experts and approved by our research committee and our panel of people living with diabetes. So you're supporting research of the highest scientific quality, led by researchers with the skills and experience to succeed.

Your support of our research projects means we can keep tackling the complications of diabetes and bring us one step closer to a cure.

Find a research project

Use the search tool to discover research taking place in your local area, or choose a subject or type of diabetes you’re interested in.

Each project page showcases the details of the research, and if you find a research project you could really get behind, you can support it in lots of different ways.

15 results found

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Region
Subject

Lymphatics: a new treatment target for kidney disease in people with diabetes?

Project:
London
Status:
Project available for adoption
Tags:
Complications
London
England
Type 1 and Type 2
Project Summary

Dr David Long and his colleagues are investigating the function of kidney lymphatic vessels in diabetic kidney disease. This will help us to understand whether targeting lymphatic vessels could be a novel treatment strategy for diabetic kidney disease. 

Can self-management therapies help with chronic pain?

Project:
London
Status:
Project available for adoption
Tags:
Complications
England
London
Type 1 and Type 2
Project Summary

Current treatment options for chronic pain in diabetes (also called painful diabetic neuropathy) are not very effective. A PhD student in Professor McCracken’s lab will investigate whether self-management strategies that focus around psychology could be used to manage pain better.

If successful, it will form a base for developing psychological therapies for people with painful diabetic neuropathy.

The inner workings of blood vessels

Project:
England – London
Status:
Project available for adoption
Tags:
Complications
Innovation
England
London
Type 1
Type 1 and Type 2
Type 2
Project Summary

Cells that line the inside of blood vessels can become damaged in people with diabetes. Dr Aranzazu Chamorro Jorganes is zooming in on the careful balance of molecules inside those cells, to find out how diabetes throws the balance off. Understanding more about blood vessel damage on a molecular level could uncover new ways to restore blood vessels back to full health in people with diabetes.

Avoiding serious long-term illnesses in Type 2 diabetes

Project:
London
Status:
Project available for adoption
Tags:
Complications
London
England
Type 2
Partnership
Project Summary

There are still many unanswered questions in Type 2 diabetes. How do blood glucose levels change as diabetes progresses and why are women and ethnic minorities with diabetes more susceptible to heart disease?

Professor Nishi Chaturvedi will be using data from the UK Biobank to tackle these questions. She hopes her research could lead to improved diagnosis and personalised treatments, and could also help people with Type 2 diabetes to avoid complications and other long-term illnesses.

Can Type 2 diabetes drugs protect against complications?

Project:
South West - Exeter
Status:
Project available for adoption
Tags:
Complications
England
England - South West
Type 1 and Type 2
Project Summary

New studies suggest that Type 2 diabetes drugs (used to control blood glucose levels) have positive effects on blood vessels. Dr Kim Gooding wants to know if they also have these positive effects in people with diabetes-related complications, such as retinopathy. In the long-term, this will tell us whether drugs currently used to treat Type 2 diabetes could also treat complications, and inform the development of new treatments to combat complications in the future.

Can new ceramic materials combat Charcot foot?

Project:
London
Status:
Project available for adoption
Tags:
Complications
London
Type 1 and Type 2
England
Project Summary

Dr Petrova is searching for a way to treat the debilitating condition known as Charcot foot, where the bones in the foot can collapse.

Her team are testing a new range of materials called bioceramics, to see if any of them can encourage healing and potentially be used as a treatment for Charcot foot in the future.

Finding new ways to stop diabetes-related kidney damage

Project:
Midlands - Lincoln
Status:
Project available for adoption
Tags:
Complications
Midlands
England
Type 1 and Type 2
Project Summary

Many people with diabetes experience nephropathy – a condition that is the leading cause of end-stage kidney disease. We know that high levels of glucose can damage kidney cells, and Professor Squires hopes to find ways to stop or prevent this damage from happening. These could be developed into treatments for diabetes-related nephropathy in the future.

Type 2 drugs and cardiovascular problems

Project:
North West - Manchester
Status:
Project available for adoption
Tags:
North West
Type 2
England
Complications
Project Summary

Dr Martin Rutter will study key Type 2 diabetes drugs to find out if they are linked to cardiovascular problems. This will provide reliable and urgently needed information about the possible link between commonly prescribed Type 2 diabetes drugs and the risk of heart attack and stroke.

How does cancer affect people with Type 2?

Project:
Bristol, South West
Status:
Project available for adoption
Tags:
Complications
Type 2
South West
England
Project Summary

Dr Emma Vincent wants to understand why people with Type 2 diabetes are more likely to develop certain types of cancer than people without Type 2. She will be investigating changes inside the body that may encourage these cancers to develop. Dr Vincent hopes that by understanding these processes, we will be able to find ways to protect people with Type 2 from developing certain cancers in the future.

Splicing genes to treat kidney disease

Project:
South West - Exeter
Status:
Project available for adoption
Tags:
South West
Type 1 and Type 2
England
Complications
Project Summary

Many people with diabetes develop kidney damage. We know that a protein called VEGF plays an important role in causing this damage. But another form of VEGF protects against kidney damage. Dr Sebastian Oltean wants to find new treatments that help people with diabetes to make more protective VEGF, to slow or prevent kidney damage. 

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