Our research projects

We fund world class research

At any one time, we have around 120 research projects making discoveries across the UK. Each of these projects is only possible thanks to the generous support of our members, donors and local groups

Every project is reviewed by experts and approved by our research committee and our panel of people living with diabetes. So you're supporting research of the highest scientific quality, led by researchers with the skills and experience to succeed.

Your support of our research projects means we can keep tackling the complications of diabetes and bring us one step closer to a cure.

Find a research project

Use the search tool to discover research taking place in your local area, or choose a subject or type of diabetes you’re interested in.

Each project page showcases the details of the research, and if you find a research project you could really get behind, you can support it in lots of different ways.

45 results found

Filters
Research Area
Region
Subject

The inner workings of blood vessels

Project:
England – London
Status:
Project available for adoption
Tags:
Complications
Innovation
England
London
Type 1
Type 1 and Type 2
Type 2
Project Summary

Cells that line the inside of blood vessels can become damaged in people with diabetes. Dr Aranzazu Chamorro Jorganes is zooming in on the careful balance of molecules inside those cells, to find out how diabetes throws the balance off. Understanding more about blood vessel damage on a molecular level could uncover new ways to restore blood vessels back to full health in people with diabetes.

Earlier detection of diabetic retinopathy using non-invasive imaging

Project:
Northern Ireland - Belfast
Status:
Project available for adoption
Tags:
Complications
Type 1 and Type 2
Northern Ireland
Innovation
Project Summary

Dr Ruth Hogg and her team will develop new software to assess high resolution images of the blood vessels in the retina, produced using a new non-invasive imaging method called OCT-A.

The study will increase our understanding of the earlier stages of diabetic retinopathy and how blood vessels in the retina change, allowing for earlier diagnosis of diabetic retinopathy. 

Discovering new drugs for diabetic kidney disease

Project:
England – London
Status:
Project available for adoption
Tags:
Type 1 and Type 2
England - London
Innovation
Complications
Project Summary

Kidney disease is a complication of diabetes, which begins with damage to the filtration barrier of the kidney. At the moment, there are very few drugs which directly prevent this initial damage. Dr Long plans to screen over 1,200 potential new drugs for diabetic kidney disease, testing them in zebrafish. This could inform the development of new kidney disease treatments in the future.

Imaging the kidney in diabetes

Project:
South West - Bristol
Status:
Project has less than a year to run
Tags:
Innovation
South West
England
Type 1 and Type 2
Complications
Project Summary

Professor Coward will purchase a combined transmitted light and fluorescent microscope and an imaging computer, which will help his team to study kidney cells and drive forward their understanding of diabetic kidney disease and the development of new therapies.

Ancient medicine to treat infected foot ulcers

Project:
Midlands - Warwick
Status:
Project available for adoption
Tags:
Midlands
Type 1 and Type 2
Complications
Project Summary

Infections in foot ulcers can be hard to treat and don’t always respond to antibiotics. If this happens, they can result in amputations or sepsis.

Dr Freya Harrison wants to find new types of antibiotics that could be used to effectively treat infections in foot ulcers. In the future, this could improve the quality of people with diabetes’ lives and reduce the number of amputations.

Why do blood vessels in the kidneys narrow?

Project:
Scotland - Edinburgh
Status:
Project available for adoption
Tags:
Type 1 and Type 2
Scotland
Complications
Project Summary

People with diabetes are at a higher risk of developing kidney disease, but we don’t fully understand how it develops. Professor Matthew Bailey wants to study a specific molecule, called P2X7R, to see if it’s responsible for the narrowing of the small blood vessels at the early stages of kidney disease. This research would help us to better understand how kidney disease develops, so we can find new ways to treat it.

Treating eye complications early

Project:
Belfast
Status:
Project available for adoption
Tags:
Type 1 and Type 2
Complications
Northern Ireland
Project Summary

Retinopathy is an eye complication of diabetes and can lead to blindness. Current treatments for retinopathy only address the end-stages of the disease, when the eye is already significantly damaged. Professor Curtis and his research team want to test a new drug that could slow or stop retinopathy earlier on in its development.

Untangling the link between Type 2 diabetes and Alzheimer's disease

Project:
South East - Southampton
Status:
Project available for adoption
Tags:
England - South East
South East
Complications
Type 2
Project Summary

People with Type 2 diabetes have an increased risk of developing Alzheimer’s disease, but we don’t know why. Dr Mudher believes that Type 2 diabetes could have a negative effect on a protein in the brain, called ‘Tau’. She wants to find out more about this interaction to see if it can be stopped, to reduce the risk of Alzheimer’s disease in people with Type 2 diabetes.

Combining drugs to treat difficult to manage Type 2 diabetes

Project:
Scotland - Aberdeen
Status:
Project available for adoption
Tags:
Type 2
Scotland
Innovation
Healthcare
Rare types of diabetes
Project Summary

Lipodystrophy is a condition that causes fat to be stored differently in the liver, muscle and pancreas. This can lead to a form of Type 2 diabetes that is difficult to manage with diet. Dr Justin Rochford and his team want to investigate if medications that are used to treat the two conditions separately could be combined to manage this difficult form of Type 2 diabetes more easily.

Lymphatics: a new treatment target for kidney disease in people with diabetes?

Project:
London
Status:
Project available for adoption
Tags:
Complications
London
England
Type 1 and Type 2
Project Summary

Dr David Long and his colleagues are investigating the function of kidney lymphatic vessels in diabetic kidney disease. This will help us to understand whether targeting lymphatic vessels could be a novel treatment strategy for diabetic kidney disease. 

Brand Icons/Telephone check - FontAwesome icons/tick icons/uk