Our research projects

We fund world class research

At any one time, we have around 120 research projects making discoveries across the UK. Each of these projects is only possible thanks to the generous support of our members, donors and local groups

Every project is reviewed by experts and approved by our research committee and our panel of people living with diabetes. So you're supporting research of the highest scientific quality, led by researchers with the skills and experience to succeed.

Your support of our research projects means we can keep tackling the complications of diabetes and bring us one step closer to a cure.

Find a research project

Use the search tool to discover research taking place in your local area, or choose a subject or type of diabetes you’re interested in.

Each project page showcases the details of the research, and if you find a research project you could really get behind, you can support it in lots of different ways.

9 results found

Filters
Research Area
Region
Subject

What’s the link between ageing and Type 2 diabetes?

Project:
South East
Status:
Project available for adoption
Tags:
Type 2
England - South East
South East
Causes
Partnership
Project Summary

Changes to our insulin-producing beta cells that happen as we get older are linked to Type 2 diabetes, but we don’t yet know how or why. Professor Masashi Narita will study cells in the lab to shed light on this link. In the future, this could lead to the development of new treatments to combat the effects of ageing on beta cells, and help to prevent Type 2 diabetes.

Making immunotherapy research bigger, smarter and faster

Project:
Cardiff - Wales
Status:
Project available for adoption
Tags:
Towards a cure
Partnership
Type 1
Wales
Project Summary

Immunotherapies work by retraining the immune system, and scientists hope they could stop or prevent the immune attack behind Type 1 diabetes. They’re testing different immunotherapies right now, but we need to speed up progress. Professor Colin Dayan will expand a network of immunotherapy research teams and improve the clinical trials process to help make these treatments available for people with Type 1 as soon as possible.

Why do bone cells age earlier in Type 1 diabetes?

Project:
South East
Status:
Project available for adoption
Tags:
Type 1
Complications
England - South East
South East
Partnership
Project Summary

Bone cells appear to age earlier in people with Type 1 diabetes, which can make bone fractures more likely. Professor Lynne Cox wants to find the root cause of why bone cells age, and develop treatments that improve bone strength and prevent fractures. This could help people with Type 1 diabetes to stay healthy as they get older.

Can combinations of gut hormones treat Type 2 diabetes?

Project:
London
Status:
Project is fully funded
Tags:
Remission
Type 2
England
Partnership
Project Summary

Obesity is the biggest risk factor of Type 2 diabetes, and bariatric surgery is currently an effective treatment. A rise in the levels of particular gut hormones are seen following surgery, and Dr Salem has found that the beneficial effects of the surgery can be replicated using the gut hormones alone in animal models.

During her fellowship, Dr Salem plans to explore the underlying biology of how gut hormones effectively treat diabetes and obesity, to inform the development of combination hormone treatments that could result in diabetes remission and sustained weight loss.

New NHS teams for Type 1 vaccine trials

Project:
Wales - Cardiff
Status:
Project not available for adoption
Tags:
Prevention
Type 1
Wales
Towards a cure
Partnership
Project Summary

Professor Colin Dayan and his team will work to set up, train and maintain a network of 15 Type 1 vaccine research teams across the UK, who will help recruit for and run clinical trials of the new therapies. They will also help train the doctors and researchers who will lead trials of new immune therapies in the future.

Expert insight into Type 1 vaccine trials

Project:
England – London
Status:
Project not available for adoption
Tags:
London
Type 1
England
Prevention
Partnership
Towards a cure
Project Summary

Dr Tim Tree and researchers across the UK will set up a network of specialist labs to examine samples from all UK-based trials of immune therapies for Type 1 diabetes.

They will carry out state-of-the-art studies of their safety and effectiveness to accelerate research into new treatments.

Avoiding serious long-term illnesses in Type 2 diabetes

Project:
London
Status:
Project available for adoption
Tags:
Complications
London
England
Type 2
Partnership
Project Summary

There are still many unanswered questions in Type 2 diabetes. How do blood glucose levels change as diabetes progresses and why are women and ethnic minorities with diabetes more susceptible to heart disease?

Professor Nishi Chaturvedi will be using data from the UK Biobank to tackle these questions. She hopes her research could lead to improved diagnosis and personalised treatments, and could also help people with Type 2 diabetes to avoid complications and other long-term illnesses.

Why do some people develop Type 1 diabetes more slowly?

Project:
Bristol - South West
Status:
Project available for adoption
Tags:
England - South West
Type 1
Partnership
Causes
Project Summary

In some people, the immune attack that causes Type 1 diabetes can progress slowly from childhood. In other people, it can start later in life and progress quickly.

Dr Anna Long will study the immune systems of these different groups to find out why some people develop Type 1 diabetes more slowly. In the future, this could lead to life-changing treatments to delay or prevent Type 1 diabetes.

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