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Our research projects

We fund world class research

At any one time, we have around 120 research projects making discoveries across the UK. Each of these projects is only possible thanks to the generous support of our members, donors and local groups

Every project is reviewed by experts and approved by our research committee and our panel of people living with diabetes. So you're supporting research of the highest scientific quality, led by researchers with the skills and experience to succeed.

Your support of our research projects means we can keep tackling the complications of diabetes and bring us one step closer to a cure.
 

Find a research project

Use the search tool to discover research taking place in your local area, or choose a subject or type of diabetes you’re interested in.

Each project page showcases the details of the research, and if you find a research project you could really get behind, you can support it in lots of different ways.

6 results found

Follicular helper T cells: are they an indication of Type 1 diabetes?

Project:
London
Status:
Project not available for adoption
Tags:
Prevention
Towards a cure
Partnership
Project Summary

Professor Lucy Walker and her colleagues have found that a specific type of immune cell – called the follicular helper T cell – can trigger Type 1 diabetes in mice, and is more common in people with Type 1 diabetes.

The team now aims to understand exactly how follicular helper T cells cause Type 1 diabetes, and they will test new strategies to stop this from happening. They will test whether follicular helper T cells can be used as an early indication of the autoimmune response in Type 1 diabetes.

Can combinations of gut hormones treat Type 2 diabetes?

Project:
London
Status:
Project is fully funded
Tags:
Remission
Partnership
Project Summary

Obesity is the biggest risk factor of Type 2 diabetes, and bariatric surgery is currently an effective treatment. A rise in the levels of particular gut hormones are seen following surgery, and Dr Salem has found that the beneficial effects of the surgery can be replicated using the gut hormones alone in animal models.

During her fellowship, Dr Salem plans to explore the underlying biology of how gut hormones effectively treat diabetes and obesity, to inform the development of combination hormone treatments that could result in diabetes remission and sustained weight loss.

Avoiding serious long-term illnesses in Type 2 diabetes

Project:
London
Status:
Project available for adoption
Tags:
Complications
Partnership
Project Summary

There are still many unanswered questions in Type 2 diabetes. How do blood glucose levels change as diabetes progresses and why are women and ethnic minorities with diabetes more susceptible to heart disease?

Professor Nishi Chaturvedi will be using data from the UK Biobank to tackle these questions. She hopes her research could lead to improved diagnosis and personalised treatments, and could also help people with Type 2 diabetes to avoid complications and other long-term illnesses.

Expert insight into Type 1 vaccine trials

Project:
England – London
Status:
Project not available for adoption
Tags:
Prevention
Partnership
Towards a cure
Project Summary

Dr Tim Tree and researchers across the UK will set up a network of specialist labs to examine samples from all UK-based trials of immune therapies for Type 1 diabetes.

They will carry out state-of-the-art studies of their safety and effectiveness to accelerate research into new treatments.

New NHS teams for Type 1 vaccine trials

Project:
Wales - Cardiff
Status:
Project not available for adoption
Tags:
Prevention
Towards a cure
Partnership
Project Summary

Professor Colin Dayan and his team will work to set up, train and maintain a network of 15 Type 1 vaccine research teams across the UK, who will help recruit for and run clinical trials of the new therapies. They will also help train the doctors and researchers who will lead trials of new immune therapies in the future.

Why do some people develop Type 1 diabetes more slowly?

Project:
Bristol - South West
Status:
Project available for adoption
Tags:
Partnership
Causes
Project Summary

In some people, the immune attack that causes Type 1 diabetes can progress slowly from childhood. In other people, it can start later in life and progress quickly.

Dr Anna Long will study the immune systems of these different groups to find out why some people develop Type 1 diabetes more slowly. In the future, this could lead to life-changing treatments to delay or prevent Type 1 diabetes.

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