Researchers at The University of Roehampton & Coventry University would like to recruit people living with prediabetes (HbA1c 6- 6.4%) who are aged 18-50 to take part in an exciting new study.
The research will investigate the effects of proteins, that sense a hormone called glycogen, found in our muscle cells. Research in the lead investigator’s laboratories has demonstrated that these proteins may contribute to insulin resistance (when your body’s cells don’t respond properly to the hormone insulin). The researchers are further investigating the role of these proteins in insulin resistance. This is important as insulin resistance contributes to prediabetes.
The study will involve three visits to our laboratory at Whiteland College at the University of Roehampton, or visits to Coventry University. The first visit will last approximately 2 hours. During this time, the researchers will take data on metabolism (the body's chemical reactions) and body composition. The visit also includes an exercise assessment.
The following two visits will be used to perform a rested or exercise protocol. These will each last around 5 hours (30 minutes preparation, followed by either rest or exercise protocol (~60min max)) and a blood sugar test called an oral glucose tolerance test (~180min)). During these trials, blood and muscle tissue samples will be collected as standard practice in our laboratory.
For more information please contact Alex Rhodes rhodesa@roehampton.ac.uk.
Alex says:
"I am a doctoral researcher investigating the role of key proteins in skeletal muscle in response to exercise and insulin stimulated glucose uptake. I work under the supervision of Dr Astrid Hauge-Evans and Dr Richard Mackenzie, lead investigators for research in diabetes. Our group is a partnership between the NHS National Diabetes Prevention Programme (NDPP) providers, NHS England, University Hospital Coventry, and Warwick (UHCW), University of Roehampton, Coventry University, Birmingham University, Oxford University, and Monash University (Australia)."
